| 19. Jornada | 12.02.2022 | KV Mechelen [Sub 18] | - | KAA Gent [Sub 18] | 2:3 | ||||
| 20. Jornada | 19.02.2022 | KRC Genk [Sub 18] | - | KV Mechelen [Sub 18] | 3:2 | ||||
| 21. Jornada | 05.03.2022 | KV Mechelen [Sub 18] | - | SV Zulte Waregem [Sub 18] | 3:0 | ||||
| 24. Jornada | 26.03.2022 | Cercle Brugge [Sub 18] | - | KV Mechelen [Sub 18] | 4:1 | ||||
| 25. Jornada | 02.04.2022 | KV Mechelen [Sub 18] | - | Standard Liège [Sub 18] | 0:3 | ||||
| 15. Jornada | 09.04.2022 | Sint-Truidense VV [Sub 18] | - | KV Mechelen [Sub 18] | 2:1 |
Bélgica