| 19. Jornada | 06.02.2022 | Egnatia Rrogozhine | - | FK Kukësi | 0:2 | ||||
| 20. Jornada | 14.02.2022 | KF Tiranë | - | Egnatia Rrogozhine | 2:0 | ||||
| 21. Jornada | 19.02.2022 | Egnatia Rrogozhine | - | KF Skënderbeu | 2:0 | ||||
| 22. Jornada | 26.02.2022 | Egnatia Rrogozhine | - | KS Kastrioti | 2:1 |  |
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| 23. Jornada | 03.03.2022 | KF Laçi | - | Egnatia Rrogozhine | 0:0 | ||||
| 24. Jornada | 07.03.2022 | Egnatia Rrogozhine | - | KF Teuta Durrës | 0:1 | ||||
| 25. Jornada | 12.03.2022 | FK Partizani | - | Egnatia Rrogozhine | 2:2 | |
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| 26. Jornada | 19.03.2022 | Egnatia Rrogozhine | - | FK Vllaznia | 3:0 | ||||
| 27. Jornada | 02.04.2022 | Dinamo Tiranë | - | Egnatia Rrogozhine | 0:2 | ||||
| 28. Jornada | 09.04.2022 | FK Kukësi | - | Egnatia Rrogozhine | 1:1 | ||||
| 30. Jornada | 24.04.2022 | KF Skënderbeu | - | Egnatia Rrogozhine | 0:1 | ||||
| 31. Jornada | 30.04.2022 | KS Kastrioti | - | Egnatia Rrogozhine | 2:1 | ||||
| 32. Jornada | 04.05.2022 | Egnatia Rrogozhine | - | KF Laçi | 0:2 | ||||
| 34. Jornada | 14.05.2022 | Egnatia Rrogozhine | - | FK Partizani | 0:1 | ||||
| 35. Jornada | 21.05.2022 | FK Vllaznia | - | Egnatia Rrogozhine | 3:1 |
Macedonia del Norte