| 1. Jornada | 09.08.2020 | FK Renova | - | FC Struga | 0:0 | ||||
| 2. Jornada | 16.08.2020 | KF Shkëndija 79 | - | FC Struga | 2:0 | ||||
| 3. Jornada | 23.08.2020 | FC Struga | - | FK Borec | 1:0 | ||||
| 4. Jornada | 29.08.2020 | FK AP Brera Strumica | - | FC Struga | 1:0 | ||||
| 5. Jornada | 12.09.2020 | FC Struga | - | Sileks Kratovo | 2:0 | ||||
| 6. Jornada | 19.09.2020 | FK Rabotnički | - | FC Struga | 1:1 | ||||
| 7. Jornada | 27.09.2020 | FC Struga | - | KF Shkupi | 2:0 | ||||
| 8. Jornada | 03.10.2020 | Makedonija GP | - | FC Struga | 2:0 | ||||
| 9. Jornada | 18.10.2020 | FC Struga | - | FK Belasica | 3:0 |  |
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| 10. Jornada | 25.10.2020 | FK Pelister | - | FC Struga | 1:1 | ||||
| 11. Jornada | 07.11.2020 | FC Struga | - | Vardar Skopje | 2:2 | ||||
| 12. Jornada | 22.11.2020 | FC Struga | - | FK Renova | 1:0 | ||||
| 13. Jornada | 29.11.2020 | FC Struga | - | KF Shkëndija 79 | 1:1 | ||||
| 17. Jornada | 13.12.2020 | FC Struga | - | FK Rabotnički | 2:1 | |
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| 18. Jornada | 16.12.2020 | KF Shkupi | - | FC Struga | 1:2 | ||||
| 19. Jornada | 21.02.2021 | FC Struga | - | Makedonija GP | 1:1 |  |
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| 20. Jornada | 28.02.2021 | FK Belasica | - | FC Struga | 1:2 | ||||
| 21. Jornada | 03.03.2021 | FC Struga | - | FK Pelister | 0:1 |
Macedonia del Norte