| 1. Jornada | 20.07.2022 | LD Alajuelense | - | Santos de Guápiles | 2:0 |  |
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| 2. Jornada | 24.07.2022 | LD Alajuelense | - | AD Guanacasteca | 4:1 | |
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| 3. Jornada | 31.07.2022 | CS Herediano | - | LD Alajuelense | 3:0 | ||||
| 4. Jornada | 07.08.2022 | Guadalupe | - | LD Alajuelense | 1:3 | ||||
| 5. Jornada | 10.08.2022 | Sporting FC | - | LD Alajuelense | 2:2 | ||||
| 6. Jornada | 14.08.2022 | Santos de Guápiles | - | LD Alajuelense | 2:1 | ||||
| 7. Jornada | 21.08.2022 | AD Guanacasteca | - | LD Alajuelense | 1:2 |  |
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| 8. Jornada | 29.08.2022 | LD Alajuelense | - | CS Herediano | 2:2 | |
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| 10. Jornada | 04.09.2022 | LD Alajuelense | - | Sporting FC | 2:1 | |
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| 11. Jornada | 11.09.2022 | LD Alajuelense | - | Deportivo Saprissa | 0:1 | ||||
| 12. Jornada | 17.09.2022 | Puntarenas FC | - | LD Alajuelense | 0:0 | ||||
| 13. Jornada | 22.09.2022 | LD Alajuelense | - | Municipal Pérez Zeledón | 1:0 | |
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| 14. Jornada | 25.09.2022 | AD San Carlos | - | LD Alajuelense | 0:0 | ||||
| 15. Jornada | 29.09.2022 | CS Cartaginés | - | LD Alajuelense | 1:2 | |
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| 16. Jornada | 02.10.2022 | LD Alajuelense | - | Municipal Grecia | 4:3 |
Panamá