| 3. Jornada | 14.08.2010 | KV Mechelen | - | Lierse SK (old) | 1:0 | ||||
| 4. Jornada | 21.08.2010 | Lierse SK (old) | - | KV Kortrijk | 1:2 | ||||
| 8. Jornada | 22.09.2010 | Lierse SK (old) | - | RSC Anderlecht | 1:1 |  |
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| 9. Jornada | 25.09.2010 | Sporting Charleroi | - | Lierse SK (old) | 0:1 | ||||
| 10. Jornada | 02.10.2010 | Lierse SK (old) | - | Cercle Brugge | 0:1 | ||||
| 11. Jornada | 16.10.2010 | Germinal Beerschot | - | Lierse SK (old) | 1:1 | ||||
| 12. Jornada | 23.10.2010 | Lierse SK (old) | - | SV Zulte Waregem | 0:0 | ||||
| 13. Jornada | 30.10.2010 | KAS Eupen | - | Lierse SK (old) | 2:2 | ||||
| 14. Jornada | 06.11.2010 | Lierse SK (old) | - | Sporting Lokeren | 2:2 | ||||
| 15. Jornada | 13.11.2010 | Club Brugge KV | - | Lierse SK (old) | 2:0 |  |
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| 16. Jornada | 20.11.2010 | Lierse SK (old) | - | Sint-Truidense VV | 1:2 |
Bélgica