| 1. Jornada | 15.09.2019 | Peñarol | - | Defensor Sporting | 1:0 |  |
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| 2. Jornada | 19.09.2019 | Cerro Largo | - | Defensor Sporting | 1:4 | |
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| 3. Jornada | 22.09.2019 | Defensor Sporting | - | Rampla Juniors | 1:0 |  |
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| 4. Jornada | 06.10.2019 | Juventud de Las Piedras | - | Defensor Sporting | 1:3 | ||||
| 5. Jornada | 11.10.2019 | Defensor Sporting | - | Liverpool | 0:0 | ||||
| 6. Jornada | 18.10.2019 | Montevideo Wanderers | - | Defensor Sporting | 2:0 | |
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| 7. Jornada | 20.10.2019 | Defensor Sporting | - | Racing | 4:0 | ||||
| 8. Jornada | 25.10.2019 | Boston River | - | Defensor Sporting | 1:4 | ||||
| 9. Jornada | 02.11.2019 | Defensor Sporting | - | Danubio | 1:2 | |
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| 11. Jornada | 10.11.2019 | Defensor Sporting | - | CA Cerro | 1:1 | ||||
| 12. Jornada | 16.11.2019 | River Plate | - | Defensor Sporting | 1:0 | ||||
| 13. Jornada | 22.11.2019 | Defensor Sporting | - | Nacional | 2:1 | ||||
| 14. Jornada | 28.11.2019 | Fénix | - | Defensor Sporting | 3:2 | |
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| 15. Jornada | 06.12.2019 | Defensor Sporting | - | Progreso | 2:4 |
Uruguay