| 1. Jornada | 20.08.2022 | Mosta FC | - | Gudja United | 1:2 |  |
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| 2. Jornada | 27.08.2022 | Marsaxlokk FC | - | Mosta FC | 1:4 |  |
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| 3. Jornada | 04.09.2022 | Mosta FC | - | Hibernians FC | 0:5 | |
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| 4. Jornada | 10.09.2022 | Pietá Hotspurs | - | Mosta FC | 1:4 | ||||
| 5. Jornada | 01.10.2022 | Mosta FC | - | Sirens FC | 1:1 | ||||
| 6. Jornada | 08.10.2022 | Floriana FC | - | Mosta FC | 1:1 | ||||
| 7. Jornada | 15.10.2022 | Mosta FC | - | Valletta FC | 3:1 | ||||
| 8. Jornada | 22.10.2022 | Hamrun Spartans | - | Mosta FC | 2:1 | ||||
| 9. Jornada | 29.10.2022 | Birkirkara FC | - | Mosta FC | 1:2 | ||||
| 10. Jornada | 04.11.2022 | Mosta FC | - | Gżira United | 0:2 | ||||
| 11. Jornada | 13.11.2022 | Balzan FC | - | Mosta FC | 1:2 | ||||
| 12. Jornada | 04.12.2022 | Mosta FC | - | Żebbuġ Rangers | 2:0 | |
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| 13. Jornada | 11.12.2022 | St. Luċija FC | - | Mosta FC | 1:2 | ||||
| 14. Jornada | 16.12.2022 | Gudja United | - | Mosta FC | 2:1 |
Ghana