| 3. Jornada | 26.02.2021 | Rosario Central II | - | Godoy Cruz II | 1:1 | ||||
| 4. Jornada | 05.03.2021 | Racing Club II | - | Rosario Central II | 2:1 | ||||
| 5. Jornada | 12.03.2021 | Rosario Central II | - | Arsenal de Sarandí II | 4:0 | ||||
| 6. Jornada | 19.03.2021 | Colón de Santa Fe II | - | Rosario Central II | 1:0 | ||||
| 7. Jornada | 26.03.2021 | Rosario Central II | - | Central Córdoba SdE II | 3:1 | ||||
| 8. Jornada | 02.04.2021 | San Lorenzo II | - | Rosario Central II | 0:0 | ||||
| 9. Jornada | 09.04.2021 | Rosario Central II | - | Banfield II | 1:1 | ||||
| 10. Jornada | 16.04.2021 | Aldosivi II | - | Rosario Central II | 1:3 | ||||
| 11. Jornada | 23.04.2021 | Rosario Central II | - | Estudiantes II | 1:3 | ||||
| 12. Jornada | 30.04.2021 | Rosario Central II | - | Newell's Old Boys II | 0:2 |
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