| 3. Jornada | 11.09.2016 | Defensor Sporting | - | Sud América | 2:0 |  |
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| 4. Jornada | 18.09.2016 | River Plate | - | Defensor Sporting | 0:5 | ||||
| 5. Jornada | 24.09.2016 | Defensor Sporting | - | CA Cerro | 0:1 | ||||
| 6. Jornada | 02.10.2016 | Defensor Sporting | - | Montevideo Wanderers | 1:1 |  |
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| 8. Jornada | 16.10.2016 | Defensor Sporting | - | Liverpool | 1:3 |  |
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| 11. Jornada | 12.11.2016 | Villa Española | - | Defensor Sporting | 2:2 | |
|
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| 14. Jornada | 04.12.2016 | Defensor Sporting | - | Racing | 2:1 | |
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| 15. Jornada | 10.12.2016 | Peñarol | - | Defensor Sporting | 0:2 |
Uruguay