| 1. Jornada | 01.07.2021 | FC Floreşti | - | CS Petrocub | 0:1 | ||||
| 2. Jornada | 17.07.2021 | FC Zimbru | - | FC Floreşti | 4:0 |  |
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| 3. Jornada | 24.07.2021 | FC Floreşti | - | Dinamo-Auto | 0:1 | ||||
| 4. Jornada | 31.07.2021 | FC Floreşti | - | FC Sheriff | 1:3 | ||||
| 5. Jornada | 08.08.2021 | FC Milsami | - | FC Floreşti | 4:1 | ||||
| 6. Jornada | 15.08.2021 | FC Floreşti | - | FC Sfîntul Gheorghe | 1:5 | ||||
| 7. Jornada | 20.08.2021 | FC Bălţi | - | FC Floreşti | 3:1 | |
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| 8. Jornada | 25.08.2021 | CS Petrocub | - | FC Floreşti | 2:0 | ||||
| 9. Jornada | 11.09.2021 | FC Floreşti | - | FC Zimbru | 1:3 | ||||
| 13. Jornada | 01.10.2021 | FC Sfîntul Gheorghe | - | FC Floreşti | 4:1 | ||||
| 14. Jornada | 16.10.2021 | FC Floreşti | - | FC Bălţi | 1:3 | ||||
| 15. Jornada | 23.10.2021 | FC Floreşti | - | CS Petrocub | 3:4 | ||||
| 16. Jornada | 30.10.2021 | FC Zimbru | - | FC Floreşti | 3:0 | ||||
| 17. Jornada | 06.11.2021 | FC Floreşti | - | Dinamo-Auto | 1:5 | ||||
| 18. Jornada | 20.11.2021 | FC Floreşti | - | FC Sheriff | 1:3 | ||||
| 19. Jornada | 28.11.2021 | FC Milsami | - | FC Floreşti | 5:0 |
Moldavia
Rumania