| 1. Jornada | 12.12.2020 | Al Mokawloon | - | Zamalek | 0:2 | ||||
| 2. Jornada | 17.12.2020 | Pyramids FC | - | Zamalek | 1:1 | ||||
| 3. Jornada | 28.12.2020 | Smouha Sporting Club | - | Zamalek | 0:2 | ||||
| 12. Jornada | 07.02.2021 | Zamalek | - | Ittihad El Iskandary | 2:0 | ||||
| 13. Jornada | 17.02.2021 | Zamalek | - | Ismaily | 2:1 | ||||
| 4. Jornada | 18.04.2021 | Zamalek | - | Al Ahly SC | 1:2 | ||||
| 16. Jornada | 22.04.2021 | El Entag El Harby | - | Zamalek | 0:2 |  |
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| 17. Jornada | 26.04.2021 | Zamalek | - | National Bank SC | 4:1 | |
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| 18. Jornada | 29.04.2021 | Zamalek | - | Al Mokawloon | 2:2 | ||||
| 19. Jornada | 02.05.2021 | Zamalek | - | Pyramids FC | 1:1 | ||||
| 20. Jornada | 06.05.2021 | Zamalek | - | Smouha Sporting Club | 2:1 | ||||
| 21. Jornada | 10.05.2021 | Al Ahly SC | - | Zamalek | 1:1 | ||||
| 22. Jornada | 14.05.2021 | Zamalek | - | ENPPI | 3:1 | ||||
| 34. Jornada | 27.08.2021 | National Bank SC | - | Zamalek | 1:1 |
Marruecos