| 6. Jornada | 28.08.2021 | Deportivo Toluca [Sub 16] | - | Puebla FC [Sub 16] | 3:0 | ||||
| 8. Jornada | 11.09.2021 | Deportivo Toluca [Sub 16] | - | CF América [Sub 16] | 1:0 | ||||
| 2. Jornada | 15.09.2021 | Club Tijuana [Sub 16] | - | Deportivo Toluca [Sub 16] | 3:0 |  |
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| 17. Jornada | 13.11.2021 | Deportivo Toluca [Sub 16] | - | CF Pachuca [Sub 16] | 4:1 |
México