| 11. Jornada | 08.10.2022 | RFC Seraing | - | KV Oostende | 1:1 | ||||
| 12. Jornada | 16.10.2022 | KV Oostende | - | Union Saint-Gilloise | 1:6 | ||||
| 13. Jornada | 20.10.2022 | Royal Antwerp FC | - | KV Oostende | 3:0 | ||||
| 14. Jornada | 23.10.2022 | KV Oostende | - | SV Zulte Waregem | 2:1 |  |
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| 15. Jornada | 29.10.2022 | Club Brugge KV | - | KV Oostende | 4:2 | ||||
| 16. Jornada | 06.11.2022 | KV Oostende | - | KV Kortrijk | 3:1 | ||||
| 17. Jornada | 12.11.2022 | KVC Westerlo | - | KV Oostende | 6:0 | ||||
| 18. Jornada | 26.12.2022 | Union Saint-Gilloise | - | KV Oostende | 3:0 | ||||
| 19. Jornada | 07.01.2023 | KV Oostende | - | RFC Seraing | 1:2 |  |
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| 21. Jornada | 18.01.2023 | KV Oostende | - | Royal Antwerp FC | 0:3 | ||||
| 24. Jornada | 03.02.2023 | KV Oostende | - | RSC Anderlecht | 0:2 |
Bélgica