| 1. Jornada | 07.03.2022 | Paphos FC | - | Apollon Limassol | 0:0 | ||||
| 2. Jornada | 13.03.2022 | Apollon Limassol | - | Anorthosis Famagusta | 1:1 | ||||
| 3. Jornada | 20.03.2022 | APOEL Nikosia | - | Apollon Limassol | 0:0 |  |
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| 4. Jornada | 03.04.2022 | Apollon Limassol | - | Aris Limassol | 1:1 | ||||
| 5. Jornada | 09.04.2022 | AEK Larnaca | - | Apollon Limassol | 3:3 | ||||
| 6. Jornada | 16.04.2022 | Apollon Limassol | - | Paphos FC | 0:2 | ||||
| 7. Jornada | 30.04.2022 | Anorthosis Famagusta | - | Apollon Limassol | 1:1 | ||||
| 8. Jornada | 08.05.2022 | Apollon Limassol | - | APOEL Nikosia | 3:2 | ||||
| 9. Jornada | 15.05.2022 | Aris Limassol | - | Apollon Limassol | 1:4 |
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