| 2. Jornada | 12.09.2021 | AEK Larnaca | - | Omonia Nikosia | 2:1 | ||||
| 3. Jornada | 20.09.2021 | Omonia Nikosia | - | Doxa Katokopias | 2:1 | ||||
| 4. Jornada | 26.09.2021 | Omonia Nikosia | - | Paphos FC | 1:1 | ||||
| 5. Jornada | 03.10.2021 | Olympiacos Nikosia | - | Omonia Nikosia | 1:0 | ||||
| 6. Jornada | 17.10.2021 | Omonia Nikosia | - | Apollon Limassol | 1:0 | ||||
| 8. Jornada | 29.10.2021 | Omonia Nikosia | - | Anorthosis Famagusta | 0:1 | ||||
| 14. Jornada | 19.12.2021 | Doxa Katokopias | - | Omonia Nikosia | 2:1 | ||||
| 15. Jornada | 05.01.2022 | Paphos FC | - | Omonia Nikosia | 1:1 | ||||
| 16. Jornada | 10.01.2022 | Omonia Nikosia | - | Olympiacos Nikosia | 1:0 |
Nigeria