| 1. Jornada | 17.08.2022 | KF Shkëndija 79 | - | FK Skopje | 2:0 | ||||
| 3. Jornada | 21.08.2022 | Sileks Kratovo | - | FK Skopje | 3:1 | ||||
| 4. Jornada | 28.08.2022 | FK Skopje | - | KF Shkupi | 0:2 | ||||
| 5. Jornada | 31.08.2022 | FK AP Brera Strumica | - | FK Skopje | 3:0 | ||||
| 6. Jornada | 04.09.2022 | FK Skopje | - | FK Pobeda Junior | 1:0 | ||||
| 7. Jornada | 11.09.2022 | FC Struga | - | FK Skopje | 3:0 | ||||
| 8. Jornada | 18.09.2022 | FK Skopje | - | FK Bregalnica Štip | 0:0 | ||||
| 9. Jornada | 02.10.2022 | GFK Tikvesh | - | FK Skopje | 2:0 |  |
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| 10. Jornada | 09.10.2022 | FK Skopje | - | FK Rabotnički | 0:0 | |
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| 11. Jornada | 15.10.2022 | Makedonija GP | - | FK Skopje | 2:0 | ||||
| 14. Jornada | 05.11.2022 | FK Skopje | - | Sileks Kratovo | 0:0 | ||||
| 15. Jornada | 12.11.2022 | KF Shkupi | - | FK Skopje | 3:1 | ||||
| 16. Jornada | 27.11.2022 | FK Skopje | - | FK AP Brera Strumica | 2:1 | ||||
| 17. Jornada | 04.12.2022 | FK Pobeda Junior | - | FK Skopje | 0:0 |
Macedonia del Norte