| 1. Jornada | 01.08.2021 | AD Chalatenango | - | Platense Zacatecoluca | 2:2 | ||||
| 4. Jornada | 15.08.2021 | Santa Tecla FC | - | AD Chalatenango | 1:1 | ||||
| 6. Jornada | 26.08.2021 | CD Águila | - | AD Chalatenango | 2:1 | ||||
| 7. Jornada | 29.08.2021 | AD Chalatenango | - | Once Municipal | 1:2 |  |
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| 8. Jornada | 11.09.2021 | Jocoro FC | - | AD Chalatenango | 3:1 | ||||
| 10. Jornada | 19.09.2021 | AD Chalatenango | - | Municipal Limeño | 1:1 | ||||
| 11. Jornada | 26.09.2021 | Isidro Metapán | - | AD Chalatenango | 1:4 | ||||
| 12. Jornada | 02.10.2021 | Platense Zacatecoluca | - | AD Chalatenango | 2:1 | ||||
| 13. Jornada | 18.10.2021 | AD Chalatenango | - | Atlético Marte | 2:2 | ||||
| 16. Jornada | 31.10.2021 | Luis Ángel Firpo | - | AD Chalatenango | 4:2 | ||||
| 17. Jornada | 03.11.2021 | AD Chalatenango | - | CD Águila | 1:1 | ||||
| 18. Jornada | 07.11.2021 | Once Municipal | - | AD Chalatenango | 1:2 |
El Salvador