| 1. Jornada | 14.08.2021 | Floriana FC | - | St. Luċija FC | 2:2 | ||||
| 3. Jornada | 12.09.2021 | Gudja United | - | St. Luċija FC | 2:2 | ||||
| 4. Jornada | 18.09.2021 | St. Luċija FC | - | Sirens FC | 1:3 | ||||
| 6. Jornada | 17.10.2021 | St. Luċija FC | - | Mosta FC | 2:2 | ||||
| 7. Jornada | 24.10.2021 | St. Luċija FC | - | Sliema Wanderers | 0:0 | ||||
| 17. Jornada | 05.02.2022 | Mosta FC | - | St. Luċija FC | 1:0 |
Malta