| 5. Jornada | 13.02.2022 | Honduras Progreso | - | Marathón | 2:1 |  |
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| 10. Jornada | 13.03.2022 | Honduras Progreso | - | Olimpia | 1:3 | ||||
| 11. Jornada | 20.03.2022 | Lobos UPNFM | - | Honduras Progreso | 2:2 | ||||
| 14. Jornada | 10.04.2022 | Honduras Progreso | - | Vida | 3:1 | ||||
| 16. Jornada | 21.04.2022 | Motagua | - | Honduras Progreso | 3:2 |  |
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| 17. Jornada | 24.04.2022 | Honduras Progreso | - | Real España | 1:1 | ||||
| 18. Jornada | 01.05.2022 | Honduras Progreso | - | Platense | 3:1 |
Honduras