| 3. Jornada | 04.08.2001 | Santos Laguna | - | Reboceros de la Piedad | 6:4 |  |
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| 6. Jornada | 18.08.2001 | Club León | - | Santos Laguna | 4:2 | |
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| 7. Jornada | 24.08.2001 | Santos Laguna | - | Club Necaxa | 2:2 | ||||
| 8. Jornada | 07.09.2001 | Deportivo Toluca | - | Santos Laguna | 6:2 | ||||
| 5. Jornada | 11.09.2001 | Santos Laguna | - | Pumas UNAM | 1:0 | ||||
| 9. Jornada | 15.09.2001 | Santos Laguna | - | CF Monterrey | 5:0 | |
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| 10. Jornada | 22.09.2001 | Atletico Celaya | - | Santos Laguna | 1:3 | |
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| 4. Jornada | 26.09.2001 | Cruz Azul | - | Santos Laguna | 0:0 | ||||
| 11. Jornada | 29.09.2001 | Santos Laguna | - | Deportivo Guadalajara | 0:1 | ||||
| 13. Jornada | 13.10.2001 | Puebla FC | - | Santos Laguna | 2:1 | ||||
| 14. Jornada | 19.10.2001 | Santos Laguna | - | Atlante | 2:1 | |
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| 15. Jornada | 27.10.2001 | Monarcas Morelia | - | Santos Laguna | 3:2 | |
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| 19. Jornada | 24.11.2001 | Club Irapuato | - | Santos Laguna | 1:1 |
México
Italia 
