| 4. Jornada | 31.07.2022 | Matagalpa FC | - | H&H Export Sébaco | 1:2 | ||||
| 5. Jornada | 07.08.2022 | H&H Export Sébaco | - | UNAN Managua | 5:0 | ||||
| 6. Jornada | 11.08.2022 | Club Deportivo Ocotal | - | H&H Export Sébaco | 2:1 | ||||
| 7. Jornada | 14.08.2022 | H&H Export Sébaco | - | Managua FC | 2:1 | ||||
| 8. Jornada | 20.08.2022 | Diriangén FC | - | H&H Export Sébaco | 0:0 | ||||
| 9. Jornada | 28.08.2022 | ART Municipal Jalapa | - | H&H Export Sébaco | 1:0 |  |
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| 10. Jornada | 04.09.2022 | Juventus Managua | - | H&H Export Sébaco | 1:1 | ||||
| 11. Jornada | 11.09.2022 | H&H Export Sébaco | - | CD Walter Ferretti | 1:1 | ||||
| 13. Jornada | 23.10.2022 | H&H Export Sébaco | - | Matagalpa FC | 2:1 | ||||
| 14. Jornada | 27.10.2022 | UNAN Managua | - | H&H Export Sébaco | 0:0 | ||||
| 16. Jornada | 24.11.2022 | Managua FC | - | H&H Export Sébaco | 0:1 | ||||
| 17. Jornada | 27.11.2022 | H&H Export Sébaco | - | Diriangén FC | 0:3 |
Nicaragua