| 3. Jornada | 31.01.2021 | Chinandega | - | Managua FC | 1:1 | ||||
| 5. Jornada | 07.02.2021 | Juventus Managua | - | Managua FC | 0:5 | ||||
| 8. Jornada | 18.02.2021 | Managua FC | - | Diriangén FC | 1:3 | ||||
| 12. Jornada | 01.04.2021 | Managua FC | - | Chinandega | 3:1 | ||||
| 14. Jornada | 19.04.2021 | Managua FC | - | Juventus Managua | 4:1 |  |
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| 15. Jornada | 26.04.2021 | ART Municipal Jalapa | - | Managua FC | 2:2 | |
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| 18. Jornada | 07.05.2021 | Managua FC | - | Real Estelí FC | 1:0 |
Nicaragua