| 2. Jornada | 01.08.2021 | Bogotá FC | - | Barranquilla FC | 2:0 |  |
|||
| 4. Jornada | 13.08.2021 | Atlético FC | - | Bogotá FC | 0:1 | ||||
| 5. Jornada | 21.08.2021 | Bogotá FC | - | Orsomarso SC | 3:0 | |
|||
| 6. Jornada | 30.08.2021 | Valledupar FC | - | Bogotá FC | 0:2 | ||||
| 7. Jornada | 08.09.2021 | Bogotá FC | - | Boyacá Chicó | 2:1 | |
|||
| 8. Jornada | 15.09.2021 | Fortaleza FC | - | Bogotá FC | 3:0 |  |
|||
| 11. Jornada | 01.10.2021 | Bogotá FC | - | Unión Magdalena | 3:1 |  |
|||
| 12. Jornada | 08.10.2021 | Boca Juniors de Cali | - | Bogotá FC | 1:2 | |
|||
| 13. Jornada | 20.10.2021 | Bogotá FC | - | Real Cartagena | 0:0 | ||||
| 14. Jornada | 24.10.2021 | Leones FC | - | Bogotá FC | 1:0 | |
|||
| 15. Jornada | 30.10.2021 | Bogotá FC | - | Llaneros FC | 2:1 |
Colombia