| 3. Jornada | 27.08.2000 | Club Brugge KV | - | Sporting Lokeren | 3:1 |  |
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| 4. Jornada | 06.09.2000 | Standard Liège | - | Club Brugge KV | 0:4 | |
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| 5. Jornada | 10.09.2000 | Club Brugge KV | - | RAA La Louviére | 3:0 | ||||
| 6. Jornada | 17.09.2000 | Germinal Beerschot | - | Club Brugge KV | 2:3 | ||||
| 7. Jornada | 24.09.2000 | KRC Harelbeke | - | Club Brugge KV | 0:6 | |
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| 8. Jornada | 01.10.2000 | Club Brugge KV | - | KV Mechelen | 5:2 | ||||
| 9. Jornada | 15.10.2000 | K.S.C. Eendracht Aalst | - | Club Brugge KV | 0:2 | |
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| 10. Jornada | 22.10.2000 | Club Brugge KV | - | Sint-Truidense VV | 5:0 | |
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| 12. Jornada | 12.11.2000 | Club Brugge KV | - | KSK Beveren | 6:0 | ||||
| 13. Jornada | 17.11.2000 | RSC Charleroi | - | Club Brugge KV | 0:4 | ||||
| 14. Jornada | 26.11.2000 | Club Brugge KV | - | Royal Antwerp FC | 2:0 |  |
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| 15. Jornada | 01.12.2000 | RSC Anderlecht | - | Club Brugge KV | 2:0 | ||||
| 16. Jornada | 10.12.2000 | Club Brugge KV | - | Lierse SK (old) | 1:0 | ||||
| 17. Jornada | 17.12.2000 | KRC Genk | - | Club Brugge KV | 0:1 | |
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| 19. Jornada | 19.01.2001 | Club Brugge KV | - | Excelsior Mouscron | 2:2 |
Bélgica