| 1. Jornada | 13.08.2000 | K.S.C. Eendracht Aalst | - | Lierse SK (old) | 1:3 |  |
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| 2. Jornada | 19.08.2000 | Sint-Truidense VV | - | Lierse SK (old) | 0:1 | ||||
| 3. Jornada | 27.08.2000 | KVC Westerlo | - | Lierse SK (old) | 1:0 |  |
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| 4. Jornada | 06.09.2000 | Lierse SK (old) | - | KSK Beveren | 3:0 | ||||
| 5. Jornada | 09.09.2000 | RSC Charleroi | - | Lierse SK (old) | 2:0 | ||||
| 6. Jornada | 16.09.2000 | Lierse SK (old) | - | Royal Antwerp FC | 4:1 | ||||
| 11. Jornada | 27.10.2000 | Lierse SK (old) | - | Excelsior Mouscron | 1:4 | |
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| 14. Jornada | 25.11.2000 | RAA La Louviére | - | Lierse SK (old) | 0:2 | ||||
| 15. Jornada | 02.12.2000 | Lierse SK (old) | - | Germinal Beerschot | 1:1 | ||||
| 22. Jornada | 10.02.2001 | Lierse SK (old) | - | RSC Charleroi | 2:0 | ||||
| 23. Jornada | 17.02.2001 | Royal Antwerp FC | - | Lierse SK (old) | 0:0 | ||||
| 24. Jornada | 03.03.2001 | Lierse SK (old) | - | RSC Anderlecht | 0:0 | |
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| 26. Jornada | 17.03.2001 | KRC Genk | - | Lierse SK (old) | 2:0 |
Australia