| 1. Jornada | 01.08.2021 | Luis Ángel Firpo | - | Jocoro FC | 1:1 | ||||
| 2. Jornada | 08.08.2021 | Municipal Limeño | - | Luis Ángel Firpo | 1:1 | ||||
| 3. Jornada | 11.08.2021 | Luis Ángel Firpo | - | Platense Zacatecoluca | 3:2 | ||||
| 4. Jornada | 15.08.2021 | Alianza | - | Luis Ángel Firpo | 2:2 | ||||
| 5. Jornada | 22.08.2021 | AD Chalatenango | - | Luis Ángel Firpo | 0:2 | ||||
| 6. Jornada | 25.08.2021 | Luis Ángel Firpo | - | Once Municipal | 2:2 | ||||
| 7. Jornada | 29.08.2021 | FAS | - | Luis Ángel Firpo | 3:1 | ||||
| 15. Jornada | 24.10.2021 | Luis Ángel Firpo | - | Alianza | 2:1 | ||||
| 18. Jornada | 07.11.2021 | Luis Ángel Firpo | - | FAS | 2:0 | ||||
| 19. Jornada | 14.11.2021 | Isidro Metapán | - | Luis Ángel Firpo | 2:1 | ||||
| 20. Jornada | 18.11.2021 | Luis Ángel Firpo | - | Atlético Marte | 2:0 | ||||
| 21. Jornada | 21.11.2021 | Santa Tecla FC | - | Luis Ángel Firpo | 2:2 | ||||
| 22. Jornada | 27.11.2021 | Luis Ángel Firpo | - | CD Águila | 1:0 |
México