| 1. Jornada | 24.07.2021 | Club León [Sub 16] | - | Club Necaxa [Sub 16] | 1:1 | ||||
| 2. Jornada | 31.07.2021 | UANL Tigres [Sub 16] | - | Club León [Sub 16] | 3:1 |  |
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| 3. Jornada | 07.08.2021 | Club León [Sub 16] | - | Deportivo Guadalajara [Sub 16] | 1:7 | ||||
| 5. Jornada | 21.08.2021 | Club León [Sub 16] | - | CF Monterrey [Sub 16] | 0:1 | ||||
| 6. Jornada | 28.08.2021 | Atlético San Luis [Sub 16] | - | Club León [Sub 16] | 1:3 | ||||
| 7. Jornada | 04.09.2021 | Santos Laguna [Sub 16] | - | Club León [Sub 16] | 1:0 | ||||
| 8. Jornada | 11.09.2021 | Club León [Sub 16] | - | Atlas Guadalajara [Sub 16] | 2:1 |  |
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| 10. Jornada | 25.09.2021 | Club León [Sub 16] | - | UANL Tigres [Sub 16] | 1:2 |
México