| 5. Jornada | 11.02.2022 | AD San Carlos | - | CS Herediano | 1:1 | ||||
| 7. Jornada | 20.02.2022 | CS Cartaginés | - | CS Herediano | 1:0 | ||||
| 8. Jornada | 27.02.2022 | CS Herediano | - | AD Guanacasteca | 1:2 |  |
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| 9. Jornada | 03.03.2022 | CS Herediano | - | LD Alajuelense | 1:1 | |
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| 10. Jornada | 06.03.2022 | Guadalupe | - | CS Herediano | 1:1 | ||||
| 11. Jornada | 01.04.2022 | CS Herediano | - | Municipal Pérez Zeledón | 3:2 | ||||
| 12. Jornada | 05.04.2022 | Jicaral | - | CS Herediano | 0:3 | |
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| 13. Jornada | 10.04.2022 | CS Herediano | - | Municipal Grecia | 3:1 | ||||
| 14. Jornada | 18.04.2022 | CS Herediano | - | Santos de Guápiles | 3:0 | ||||
| 15. Jornada | 21.04.2022 | Deportivo Saprissa | - | CS Herediano | 0:1 | ||||
| 16. Jornada | 24.04.2022 | CS Herediano | - | AD San Carlos | 1:1 | ||||
| 17. Jornada | 28.04.2022 | Sporting FC | - | CS Herediano | 0:2 | |
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| 18. Jornada | 01.05.2022 | CS Herediano | - | CS Cartaginés | 4:1 | |
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| 19. Jornada | 04.05.2022 | AD Guanacasteca | - | CS Herediano | 0:1 | ||||
| 20. Jornada | 09.05.2022 | LD Alajuelense | - | CS Herediano | 2:1 | ||||
| 21. Jornada | 13.05.2022 | CS Herediano | - | Guadalupe | 0:0 |  |
Costa Rica