| 1. Jornada | 13.07.2019 | Guaraní | - | River Plate | 1:3 | ||||
| 2. Jornada | 21.07.2019 | Libertad | - | Guaraní | 1:0 | ||||
| 3. Jornada | 28.07.2019 | Guaraní | - | Sportivo Luqueño | 1:3 | ||||
| 6. Jornada | 18.08.2019 | Deportivo Capiatá | - | Guaraní | 1:2 | ||||
| 7. Jornada | 25.08.2019 | Guaraní | - | San Lorenzo | 3:1 | ||||
| 8. Jornada | 02.09.2019 | Guaraní | - | General Díaz | 5:0 | ||||
| 9. Jornada | 15.09.2019 | Sol de América | - | Guaraní | 0:1 | ||||
| 10. Jornada | 22.09.2019 | Guaraní | - | Club Olimpia | 1:1 |  |
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| 11. Jornada | 25.09.2019 | Club Nacional | - | Guaraní | 0:2 | ||||
| 12. Jornada | 29.09.2019 | River Plate | - | Guaraní | 0:1 | ||||
| 13. Jornada | 05.10.2019 | Guaraní | - | Libertad | 1:1 |  |
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| 16. Jornada | 31.10.2019 | Deportivo Santaní | - | Guaraní | 2:1 | ||||
| 17. Jornada | 24.11.2019 | Guaraní | - | Deportivo Capiatá | 2:1 | ||||
| 20. Jornada | 01.12.2019 | Guaraní | - | Sol de América | 0:1 | ||||
| 21. Jornada | 08.12.2019 | Club Olimpia | - | Guaraní | 2:2 | |
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| 22. Jornada | 15.12.2019 | Guaraní | - | Club Nacional | 0:5 |
Uruguay