| 1. Jornada | 16.01.2011 | Club Aurora | - | Club San José | 1:1 |  |
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| 2. Jornada | 23.01.2011 | Club San José | - | Universitario de Sucre | 2:1 | ||||
| 7. Jornada | 24.02.2011 | La Paz FC | - | Club San José | 1:0 | |
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| 8. Jornada | 26.02.2011 | Club San José | - | Real Potosí | 2:1 | ||||
| 9. Jornada | 13.03.2011 | The Strongest | - | Club San José | 0:0 | |
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| 10. Jornada | 20.03.2011 | Club San José | - | Blooming | 2:1 | |
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| 12. Jornada | 10.04.2011 | Club San José | - | Club Aurora | 1:0 | ||||
| 13. Jornada | 17.04.2011 | Universitario de Sucre | - | Club San José | 0:1 | ||||
| 14. Jornada | 20.04.2011 | Club San José | - | Nacional Potosí | 1:1 | ||||
| 16. Jornada | 01.05.2011 | Club San José | - | Oriente Petrolero | 1:0 | ||||
| 17. Jornada | 08.05.2011 | Real Mamoré | - | Club San José | 2:0 | |
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| 19. Jornada | 15.05.2011 | Real Potosí | - | Club San José | 1:1 | ||||
| 20. Jornada | 19.05.2011 | Club San José | - | The Strongest | 2:1 | ||||
| 21. Jornada | 22.05.2011 | Blooming | - | Club San José | 2:1 |
Bolivia