| 5. Jornada | 31.08.2020 | Santa Cruz | - | Deportes Melipilla | 2:4 | ||||
| 6. Jornada | 05.09.2020 | Deportes Melipilla | - | Unión San Felipe | 0:1 | ||||
| 10. Jornada | 22.09.2020 | Barnechea | - | Deportes Melipilla | 0:1 |  |
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| 11. Jornada | 27.09.2020 | Deportes Melipilla | - | Ñublense | 1:0 | ||||
| 12. Jornada | 01.10.2020 | CD Magallanes | - | Deportes Melipilla | 0:0 | ||||
| 13. Jornada | 05.10.2020 | Deportes Melipilla | - | Santiago Morning | 1:1 | |
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| 14. Jornada | 08.10.2020 | Deportes Melipilla | - | Puerto Montt | 2:0 | |
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| 15. Jornada | 12.10.2020 | Deportes Temuco | - | Deportes Melipilla | 0:3 | ||||
| 16. Jornada | 28.10.2020 | Deportes Melipilla | - | Deportes Copiapó | 1:2 | ||||
| 17. Jornada | 04.11.2020 | Ñublense | - | Deportes Melipilla | 4:0 | |
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| 18. Jornada | 08.11.2020 | Deportes Melipilla | - | San Luis | 3:0 | |
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| 19. Jornada | 12.11.2020 | Puerto Montt | - | Deportes Melipilla | 0:0 | ||||
| 20. Jornada | 17.11.2020 | Deportes Melipilla | - | CD Magallanes | 0:0 | ||||
| 28. Jornada | 30.12.2020 | Cobreloa | - | Deportes Melipilla | 0:0 |  |
Chile