| 1. Jornada | 20.01.2022 | Honduras Progreso | - | Motagua | 2:1 | ||||
| 2. Jornada | 23.01.2022 | Honduras Progreso | - | Lobos UPNFM | 1:2 | ||||
| 3. Jornada | 06.02.2022 | Olimpia | - | Honduras Progreso | 3:0 | ||||
| 4. Jornada | 10.02.2022 | Real Sociedad | - | Honduras Progreso | 4:2 | ||||
| 8. Jornada | 04.03.2022 | Honduras Progreso | - | Victoria | 2:1 | ||||
| 9. Jornada | 07.03.2022 | Platense | - | Honduras Progreso | 0:0 | ||||
| 12. Jornada | 03.04.2022 | Honduras Progreso | - | Real Sociedad | 0:1 | ||||
| 14. Jornada | 10.04.2022 | Honduras Progreso | - | Vida | 3:1 | ||||
| 16. Jornada | 21.04.2022 | Motagua | - | Honduras Progreso | 3:2 |
Honduras