| 1. Jornada | 03.07.2022 | Cusco FC | - | Unión Comercio | 4:1 |  |
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| 3. Jornada | 17.07.2022 | Alfonso Ugarte | - | Cusco FC | 0:1 | |
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| 4. Jornada | 23.07.2022 | Cusco FC | - | Chavelines Juniors | 3:0 | ||||
| 5. Jornada | 31.07.2022 | Pirata | - | Cusco FC | 2:2 | ||||
| 6. Jornada | 06.08.2022 | Cusco FC | - | Llacuabamba | 2:0 | ||||
| 7. Jornada | 14.08.2022 | Los Chankas | - | Cusco FC | 1:1 |  |
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| 8. Jornada | 21.08.2022 | Cusco FC | - | Santos FC | 4:1 | |
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| 9. Jornada | 27.08.2022 | Deportivo Coopsol | - | Cusco FC | 1:2 | |
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| 10. Jornada | 04.09.2022 | Cusco FC | - | Unión Huaral | 2:0 | |
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| 12. Jornada | 18.09.2022 | Cusco FC | - | Alianza Universidad | 2:1 | |
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| 13. Jornada | 25.09.2022 | Comerciantes Unidos | - | Cusco FC | 2:1 | |
Panamá