| 2. Jornada | 23.02.2020 | Defensor Sporting | - | Peñarol | 2:1 |  |
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| 3. Jornada | 08.03.2020 | River Plate | - | Defensor Sporting | 1:1 | ||||
| 4. Jornada | 08.08.2020 | Defensor Sporting | - | Montevideo City Torque | 0:2 | ||||
| 5. Jornada | 14.08.2020 | Plaza Colonia | - | Defensor Sporting | 2:0 | ||||
| 6. Jornada | 19.08.2020 | Defensor Sporting | - | Progreso | 2:1 | ||||
| 7. Jornada | 23.08.2020 | Fénix | - | Defensor Sporting | 5:0 | ||||
| 8. Jornada | 27.08.2020 | Defensor Sporting | - | CA Cerro | 1:1 | |
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| 9. Jornada | 30.08.2020 | Liverpool | - | Defensor Sporting | 1:2 | ||||
| 12. Jornada | 13.09.2020 | Boston River | - | Defensor Sporting | 1:1 | ||||
| 13. Jornada | 20.09.2020 | Defensor Sporting | - | Deportivo Maldonado | 4:2 | ||||
| 14. Jornada | 07.10.2020 | Rentistas | - | Defensor Sporting | 2:0 |  |
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