| 1. Jornada | 03.07.2022 | Atlético San Luis [Sub 18] | - | Club León [Sub 18] | 1:1 | ||||
| 2. Jornada | 10.07.2022 | Club León [Sub 18] | - | Pumas UNAM [Sub 18] | 1:2 | ||||
| 3. Jornada | 15.07.2022 | Puebla FC [Sub 18] | - | Club León [Sub 18] | 4:2 |  |
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| 4. Jornada | 20.07.2022 | Deportivo Guadalajara [Sub 18] | - | Club León [Sub 18] | 2:2 | ||||
| 12. Jornada | 02.09.2022 | Club Necaxa [Sub 18] | - | Club León [Sub 18] | 1:1 | ||||
| 13. Jornada | 06.09.2022 | Club León [Sub 18] | - | FC Juárez [Sub 18] | 0:0 | ||||
| 14. Jornada | 10.09.2022 | UANL Tigres [Sub 18] | - | Club León [Sub 18] | 3:1 | ||||
| 7. Jornada | 13.09.2022 | CF Monterrey [Sub 18] | - | Club León [Sub 18] | 2:0 | ||||
| 15. Jornada | 18.09.2022 | Club León [Sub 18] | - | Gallos Blancos [Sub 18] | 1:1 | ||||
| 8. Jornada | 27.09.2022 | Club León [Sub 18] | - | Mazatlán FC [Sub 18] | 2:2 | ||||
| 17. Jornada | 02.10.2022 | Club León [Sub 18] | - | Club Tijuana [Sub 18] | 0:1 |
México