| 1. Jornada | 02.07.2022 | CF América [Sub 20] | - | Atlas Guadalajara [Sub 20] | 3:0 | ||||
| 4. Jornada | 23.07.2022 | Club Tijuana [Sub 20] | - | CF América [Sub 20] | 3:3 | ||||
| 6. Jornada | 31.07.2022 | Club León [Sub 20] | - | CF América [Sub 20] | 1:0 |  |
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| 7. Jornada | 07.08.2022 | CF América [Sub 20] | - | FC Juárez [Sub 20] | 1:1 | |
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| 8. Jornada | 13.08.2022 | Pumas UNAM [Sub 20] | - | CF América [Sub 20] | 1:1 | ||||
| 9. Jornada | 17.08.2022 | CF Pachuca [Sub 20] | - | CF América [Sub 20] | 0:0 | ||||
| 10. Jornada | 20.08.2022 | CF América [Sub 20] | - | Cruz Azul [Sub 20] | 2:0 | |
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| 12. Jornada | 03.09.2022 | CF América [Sub 20] | - | UANL Tigres [Sub 20] | 1:2 | |
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| 15. Jornada | 17.09.2022 | CF América [Sub 20] | - | Deportivo Guadalajara [Sub 20] | 2:2 |
México