| 10. Jornada | 05.03.2021 | Puebla FC [Sub 20] | - | UANL Tigres [Sub 20] | 3:2 | ||||
| 1. Jornada | 27.03.2021 | Puebla FC [Sub 20] | - | Deportivo Guadalajara [Sub 20] | 2:4 | ||||
| 13. Jornada | 02.04.2021 | Puebla FC [Sub 20] | - | Mazatlán FC [Sub 20] | 6:2 | ||||
| 14. Jornada | 12.04.2021 | CF Pachuca [Sub 20] | - | Puebla FC [Sub 20] | 5:2 | ||||
| 15. Jornada | 17.04.2021 | Atlético San Luis [Sub 20] | - | Puebla FC [Sub 20] | 5:3 | ||||
| 17. Jornada | 02.05.2021 | Santos Laguna [Sub 20] | - | Puebla FC [Sub 20] | 2:3 |
México