| 1. Jornada | 25.06.2022 | Mazatlán FC [] | - | Club Tijuana [] | 0:3 | ||||
| 2. Jornada | 02.07.2022 | Club Tijuana [] | - | Santos Laguna [] | 2:0 | ||||
| 3. Jornada | 09.07.2022 | Atlas Guadalajara [] | - | Club Tijuana [] | 0:0 | ||||
| 6. Jornada | 31.07.2022 | Club Tijuana [] | - | Deportivo Guadalajara [] | 3:1 | ||||
| 9. Jornada | 20.08.2022 | Club Tijuana [] | - | Atlético San Luis [] | 6:3 |  |
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| 10. Jornada | 27.08.2022 | Club Tijuana [] | - | Mazatlán FC [] | 4:0 | ||||
| 11. Jornada | 03.09.2022 | Atlético San Luis [] | - | Club Tijuana [] | 0:2 | ||||
| 15. Jornada | 12.10.2022 | Club Tijuana [] | - | Club León [] | 5:1 | ||||
| 18. Jornada | 22.10.2022 | Santos Laguna [] | - | Club Tijuana [] | 1:0 |
México