| 1. Jornada | 04.01.2014 | Santos Laguna | - | Deportivo Guadalajara | 1:1 |  |
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| 2. Jornada | 12.01.2014 | Cruz Azul | - | Santos Laguna | 2:1 | |
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| 3. Jornada | 18.01.2014 | Santos Laguna | - | Puebla FC | 0:0 | ||||
| 4. Jornada | 25.01.2014 | Gallos Blancos | - | Santos Laguna | 0:0 | ||||
| 5. Jornada | 02.02.2014 | Santos Laguna | - | Deportivo Toluca | 2:0 | ||||
| 6. Jornada | 09.02.2014 | UANL Tigres | - | Santos Laguna | 1:1 | ||||
| 7. Jornada | 15.02.2014 | Santos Laguna | - | Club Tijuana | 3:2 |  |
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| 8. Jornada | 23.02.2014 | Club León | - | Santos Laguna | 4:2 | ||||
| 9. Jornada | 01.03.2014 | Santos Laguna | - | Atlas Guadalajara | 2:3 | ||||
| 10. Jornada | 09.03.2014 | CF América | - | Santos Laguna | 2:4 | |
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| 11. Jornada | 16.03.2014 | Santos Laguna | - | CF Pachuca | 3:1 | ||||
| 12. Jornada | 22.03.2014 | Monarcas Morelia | - | Santos Laguna | 2:2 | |
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| 13. Jornada | 29.03.2014 | Santos Laguna | - | Pumas UNAM | 2:1 | ||||
| 14. Jornada | 06.04.2014 | CF Monterrey | - | Santos Laguna | 2:2 | |
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| 15. Jornada | 14.04.2014 | Santos Laguna | - | Atlante | 4:3 | ||||
| 17. Jornada | 27.04.2014 | CD Veracruz | - | Santos Laguna | 2:2 |
México