| 2. Jornada | 01.08.2010 | Real Mamoré | - | Jorge Wilstermann | 0:0 |  |
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| 3. Jornada | 08.08.2010 | Jorge Wilstermann | - | Club San José | 1:3 | ||||
| 4. Jornada | 15.08.2010 | Universitario de Sucre | - | Jorge Wilstermann | 1:1 | ||||
| 5. Jornada | 22.08.2010 | Jorge Wilstermann | - | Blooming | 0:1 | ||||
| 6. Jornada | 29.08.2010 | Jorge Wilstermann | - | La Paz FC | 4:2 | ||||
| 7. Jornada | 04.09.2010 | The Strongest | - | Jorge Wilstermann | 2:1 | |
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| 8. Jornada | 09.09.2010 | Jorge Wilstermann | - | CD Guabirá | 1:1 | ||||
| 10. Jornada | 19.09.2010 | Jorge Wilstermann | - | Oriente Petrolero | 4:2 |  |
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| 16. Jornada | 25.10.2010 | Blooming | - | Jorge Wilstermann | 3:0 | ||||
| 13. Jornada | 28.10.2010 | Jorge Wilstermann | - | Real Mamoré | 2:0 | |
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| 18. Jornada | 31.10.2010 | Jorge Wilstermann | - | The Strongest | 3:1 | |
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| 17. Jornada | 03.11.2010 | La Paz FC | - | Jorge Wilstermann | 1:0 | ||||
| 19. Jornada | 06.11.2010 | CD Guabirá | - | Jorge Wilstermann | 2:1 | ||||
| 20. Jornada | 14.11.2010 | Jorge Wilstermann | - | Real Potosí | 1:1 | ||||
| 21. Jornada | 21.11.2010 | Oriente Petrolero | - | Jorge Wilstermann | 3:1 | ||||
| 22. Jornada | 28.11.2010 | Jorge Wilstermann | - | Club Aurora | 1:0 |
Uruguay