| 1. Jornada | 10.08.2008 | San Lorenzo | - | Tigre | 0:1 | ||||
| 2. Jornada | 17.08.2008 | Godoy Cruz | - | San Lorenzo | 1:2 | ||||
| 3. Jornada | 24.08.2008 | San Lorenzo | - | Estudiantes | 3:0 |  |
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| 4. Jornada | 31.08.2008 | River Plate | - | San Lorenzo | 0:0 | ||||
| 5. Jornada | 13.09.2008 | San Lorenzo | - | Rosario Central | 2:1 | ||||
| 6. Jornada | 17.09.2008 | Banfield | - | San Lorenzo | 1:3 | |
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| 7. Jornada | 20.09.2008 | San Lorenzo | - | Colón de Santa Fe | 3:0 | ||||
| 8. Jornada | 27.09.2008 | San Lorenzo | - | Arsenal de Sarandí | 2:0 | |
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| 9. Jornada | 04.10.2008 | Vélez Sarsfield | - | San Lorenzo | 0:1 | |
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| 10. Jornada | 18.10.2008 | San Lorenzo | - | San Martín de Tucumán | 1:0 | ||||
| 11. Jornada | 26.10.2008 | Racing Club | - | San Lorenzo | 2:1 | ||||
| 12. Jornada | 29.10.2008 | San Lorenzo | - | Gimnasia de La Plata | 1:1 | |
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| 14. Jornada | 09.11.2008 | San Lorenzo | - | Gimnasia de Jujuy | 2:1 | |
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| 15. Jornada | 16.11.2008 | Newell's Old Boys | - | San Lorenzo | 3:3 |  |
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| 17. Jornada | 02.12.2008 | Huracán | - | San Lorenzo | 1:4 | ||||
| 18. Jornada | 07.12.2008 | San Lorenzo | - | Independiente | 4:1 | ||||
| 19. Jornada | 14.12.2008 | Argentinos Juniors | - | San Lorenzo | 0:1 |
Argentina