| 1. Jornada | 23.01.2022 | Tigres FC | - | Real Cartagena | 1:2 | ||||
| 2. Jornada | 30.01.2022 | Real Santander | - | Tigres FC | 0:0 | ||||
| 3. Jornada | 05.02.2022 | Tigres FC | - | Atlético FC | 1:1 | ||||
| 4. Jornada | 13.02.2022 | Leones FC | - | Tigres FC | 3:1 | ||||
| 5. Jornada | 18.02.2022 | Tigres FC | - | Bogotá FC | 3:0 |  |
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| 6. Jornada | 26.02.2022 | Orsomarso SC | - | Tigres FC | 0:2 | ||||
| 7. Jornada | 06.03.2022 | Tigres FC | - | Llaneros FC | 0:1 |
Colombia