| 4. Jornada | 14.08.2021 | Jocoro FC | - | Isidro Metapán | 1:0 | ||||
| 5. Jornada | 22.08.2021 | Atlético Marte | - | Jocoro FC | 2:1 |  |
|||
| 6. Jornada | 25.08.2021 | Jocoro FC | - | Santa Tecla FC | 2:0 | ||||
| 7. Jornada | 29.08.2021 | CD Águila | - | Jocoro FC | 2:2 | ||||
| 8. Jornada | 11.09.2021 | Jocoro FC | - | AD Chalatenango | 3:1 | ||||
| 9. Jornada | 15.09.2021 | Jocoro FC | - | Municipal Limeño | 3:1 | ||||
| 10. Jornada | 19.09.2021 | Platense Zacatecoluca | - | Jocoro FC | 1:1 | ||||
| 11. Jornada | 25.09.2021 | Jocoro FC | - | Alianza | 3:3 | ||||
| 12. Jornada | 02.10.2021 | Jocoro FC | - | Luis Ángel Firpo | 2:1 | ||||
| 20. Jornada | 17.11.2021 | Municipal Limeño | - | Jocoro FC | 0:0 | ||||
| 21. Jornada | 21.11.2021 | Jocoro FC | - | Platense Zacatecoluca | 1:1 | ||||
| 22. Jornada | 27.11.2021 | Alianza | - | Jocoro FC | 2:0 |
El Salvador