| 1. Jornada | 13.08.2021 | Huesca | - | Eibar | 2:0 | ||||
| 2. Jornada | 22.08.2021 | Huesca | - | FC Cartagena | 2:0 | ||||
| 3. Jornada | 27.08.2021 | Las Palmas | - | Huesca | 2:1 | ||||
| 4. Jornada | 06.09.2021 | Huesca | - | Real Oviedo | 1:2 | ||||
| 5. Jornada | 13.09.2021 | Lugo | - | Huesca | 3:2 |  |
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| 7. Jornada | 24.09.2021 | Real Sociedad B | - | Huesca | 0:2 | ||||
| 8. Jornada | 02.10.2021 | Huesca | - | Tenerife | 1:2 | ||||
| 9. Jornada | 11.10.2021 | Zaragoza | - | Huesca | 0:0 | ||||
| 10. Jornada | 16.10.2021 | Girona | - | Huesca | 1:3 | ||||
| 11. Jornada | 19.10.2021 | Huesca | - | Málaga | 0:0 | ||||
| 13. Jornada | 30.10.2021 | Huesca | - | SD Amorebieta | 1:1 | ||||
| 14. Jornada | 02.11.2021 | Ponferradina | - | Huesca | 1:1 | ||||
| 15. Jornada | 05.11.2021 | Huesca | - | Leganés | 0:2 | |
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| 16. Jornada | 13.11.2021 | Mirandés | - | Huesca | 0:1 | |
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| 19. Jornada | 03.12.2021 | Huesca | - | Valladolid | 3:2 | ||||
| 20. Jornada | 10.12.2021 | Sporting | - | Huesca | 1:1 | ||||
| 22. Jornada | 02.01.2022 | Huesca | - | Girona | 0:1 |
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