| 1. Jornada | 17.07.2018 | 3 de Febrero | - | General Díaz | 1:1 | ||||
| 2. Jornada | 21.07.2018 | General Díaz | - | Club Olimpia | 1:1 | ||||
| 4. Jornada | 05.08.2018 | Deportivo Santaní | - | General Díaz | 3:1 | ||||
| 6. Jornada | 20.08.2018 | Deportivo Capiatá | - | General Díaz | 3:1 | ||||
| 7. Jornada | 25.08.2018 | General Díaz | - | Cerro Porteño | 1:4 | ||||
| 10. Jornada | 15.09.2018 | Libertad | - | General Díaz | 1:0 | ||||
| 13. Jornada | 07.10.2018 | Club Olimpia | - | General Díaz | 2:2 |  |
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| 14. Jornada | 14.10.2018 | General Díaz | - | Club Nacional | 1:2 | ||||
| 15. Jornada | 20.10.2018 | General Díaz | - | Deportivo Santaní | 4:0 | |
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| 16. Jornada | 28.10.2018 | Sportivo Luqueño | - | General Díaz | 2:0 | ||||
| 17. Jornada | 02.11.2018 | General Díaz | - | Deportivo Capiatá | 2:3 | ||||
| 18. Jornada | 11.11.2018 | Cerro Porteño | - | General Díaz | 3:1 | ||||
| 19. Jornada | 18.11.2018 | General Díaz | - | Independiente CG | 2:1 | |
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| 20. Jornada | 24.11.2018 | Guaraní | - | General Díaz | 0:2 | ||||
| 21. Jornada | 01.12.2018 | General Díaz | - | Libertad | 1:1 | |
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| 22. Jornada | 08.12.2018 | Sol de América | - | General Díaz | 1:0 |
Paraguay