| 2. Jornada | 28.01.2021 | Managua FC | - | Club Deportivo Ocotal | 3:0 | ||||
| 3. Jornada | 31.01.2021 | Chinandega | - | Managua FC | 1:1 |  |
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| 4. Jornada | 04.02.2021 | Managua FC | - | Real Madriz | 4:1 | ||||
| 6. Jornada | 11.02.2021 | Managua FC | - | ART Municipal Jalapa | 5:2 | ||||
| 8. Jornada | 18.02.2021 | Managua FC | - | Diriangén FC | 1:3 |  |
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| 14. Jornada | 19.04.2021 | Managua FC | - | Juventus Managua | 4:1 |  |
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| 18. Jornada | 07.05.2021 | Managua FC | - | Real Estelí FC | 1:0 |
Nicaragua