| 9. Jornada | 16.10.2021 | KV Mechelen [Sub 18] | - | Royal Antwerp FC [Sub 18] | 1:0 | ||||
| 10. Jornada | 23.10.2021 | KVC Westerlo [Sub 18] | - | KV Mechelen [Sub 18] | 0:5 | ||||
| 19. Jornada | 12.02.2022 | KV Mechelen [Sub 18] | - | KAA Gent [Sub 18] | 2:3 | ||||
| 20. Jornada | 19.02.2022 | KRC Genk [Sub 18] | - | KV Mechelen [Sub 18] | 3:2 | ||||
| 12. Jornada | 26.02.2022 | Standard Liège [Sub 18] | - | KV Mechelen [Sub 18] | 1:1 |  |
|||
| 23. Jornada | 19.03.2022 | KV Mechelen [Sub 18] | - | KVC Westerlo [Sub 18] | 3:1 | ||||
| 24. Jornada | 26.03.2022 | Cercle Brugge [Sub 18] | - | KV Mechelen [Sub 18] | 4:1 | ||||
| 25. Jornada | 02.04.2022 | KV Mechelen [Sub 18] | - | Standard Liège [Sub 18] | 0:3 | ||||
| 15. Jornada | 09.04.2022 | Sint-Truidense VV [Sub 18] | - | KV Mechelen [Sub 18] | 2:1 | |
|||
| 26. Jornada | 23.04.2022 | Oud-Heverlee Leuven [Sub 18] | - | KV Mechelen [Sub 18] | 2:2 |
Bélgica