| 18. Jornada | 23.12.2022 | KV Mechelen | - | Cercle Brugge | 1:1 |  |
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| 20. Jornada | 14.01.2023 | KV Mechelen | - | KV Oostende | 2:1 | ||||
| 21. Jornada | 17.01.2023 | Standard Liège | - | KV Mechelen | 2:0 | ||||
| 22. Jornada | 21.01.2023 | KV Mechelen | - | KV Kortrijk | 3:2 |  |
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| 23. Jornada | 28.01.2023 | KVC Westerlo | - | KV Mechelen | 2:0 | ||||
| 24. Jornada | 05.02.2023 | KV Mechelen | - | Sporting Charleroi | 2:2 | ||||
| 25. Jornada | 10.02.2023 | KAS Eupen | - | KV Mechelen | 2:1 | ||||
| 26. Jornada | 17.02.2023 | KV Mechelen | - | KRC Genk | 2:2 | |
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| 27. Jornada | 25.02.2023 | RFC Seraing | - | KV Mechelen | 0:2 | |
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| 28. Jornada | 05.03.2023 | Royal Antwerp FC | - | KV Mechelen | 5:0 | ||||
| 31. Jornada | 02.04.2023 | KV Mechelen | - | Club Brugge KV | 0:3 | ||||
| 32. Jornada | 08.04.2023 | Oud-Heverlee Leuven | - | KV Mechelen | 4:1 |
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