| 4. Jornada | 26.01.2021 | Guadalupe | - | Deportivo Saprissa | 2:2 | ||||
| 5. Jornada | 01.02.2021 | Santos de Guápiles | - | Guadalupe | 2:2 | ||||
| 6. Jornada | 04.02.2021 | CS Herediano | - | Guadalupe | 2:2 | ||||
| 10. Jornada | 27.02.2021 | Jicaral | - | Guadalupe | 3:2 | ||||
| 11. Jornada | 04.03.2021 | Guadalupe | - | LD Alajuelense | 1:3 | ||||
| 12. Jornada | 06.03.2021 | Limón FC | - | Guadalupe | 1:7 |  |
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| 22. Jornada | 13.05.2021 | LD Alajuelense | - | Guadalupe | 0:0 |
Costa Rica