| 9. Jornada | 16.09.2021 | AD Chalatenango | - | FAS | 1:2 | ||||
| 10. Jornada | 19.09.2021 | AD Chalatenango | - | Municipal Limeño | 1:1 | ||||
| 16. Jornada | 31.10.2021 | Luis Ángel Firpo | - | AD Chalatenango | 4:2 | ||||
| 18. Jornada | 07.11.2021 | Once Municipal | - | AD Chalatenango | 1:2 | ||||
| 19. Jornada | 14.11.2021 | AD Chalatenango | - | Jocoro FC | 2:0 |
El Salvador